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The 46th Annual Meeting of the Israel Physical Society

11th May, 2000, Technion, Haifa

IPS STUDENT PRIZEWINNERS

THEORETICAL PHYSICS - DAVID KARASIK

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David Karasik was born in 1967 in Zeriffin, Israel and after completing his military service in 1990, received B.Sc. degrees in Physics and Electrical Engineering at Ben Gurion University with grade averages of 97 and 96. Since 1995 he has been studying for a Ph.D. with Prof. A. Davidson at Ben Gurion University. He has received numerous honors, most recently a Kreitman Prize and a Fullbright Fellowship. His accepted papers include ``Quantum Gravity of a Brane-like Universe'', Mod. Phys. Lett. A13, 2187 (1998), together with A. Davidson which was honorably mentioned by The Gravity Research Foundation. David Karasik is married with four children and is a resident of Moshav Gimzo.

EXPERIMENTAL PHYSICS - DROR FIXLER

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Dror Fixler was born in 1969, and after completing his military service studied at Yeshivat Birkat Moshe in Maale Adumim from 1991-1994. He received B.Sc. and M.Sc. degrees in Physics from Bar Ilan University in 1995 and 1998, respectively. He commenced his doctoral studies under the supervision of Prof. Mordechai Deutsch at Bar Ilan in 1999. He has received several awards, including an Eshkol Scholarship from the Israel Science Ministry and currently holds a Ph.D. award from the Wolf Foundation. He already has five accepted papers, most recently ``The dynamic properties of intra cellular Ca2+ as measured of normality cardiac muscle cell by their contraction'', Eur. J. of Physiology, April 2000, together with R. Tirosh, A. Shainberg and M. Deutsch. Dror Fixler is married with two children. More details about Dror Fixler on Dror Fixler's homepage

Dror Fixler will be presenting a poster at IPS2000 in the Medical Physics section, together with Reuven Tirosh, Asher Shainberg and Motti Deutsch, entitled

``Investigation of cardiac myocyte cytoplasm structural changes during a contraction cycle by means of intracellular fluorescein fluorescence polarization.''

ABSTRACT: A simple physical model is presented. It assumes a bi-phase intracellular matrix, differing in their potency to restrict hosting fluorescent probe mobility. The first is a mobile non-restricting phase, mostly made of aqua (aqua zone), while the second is a mobile-restricting phase, allocated mainly at the proximity of the filament sites. Their physico-chemical properties such as [Ca++], viscosity and pH, may differ and thus influence differently the hosting probe fluorescence characteristics. These possible influences are experimentally examined.

Based on the experimental data, the model enables the evaluation, to first order of approximation of the relative number of fluorescent probes populating the two phases and the time variation viscosity, $\eta_{r} (t)$, of the mobile-restricting filament zones, taking place along a contraction cycle.

To the best of our knowledge, this is the first time that cardiac myocyte contraction is monitored by IFFP measurements on an individual cell basis within a population

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